What Is PrEP, and Who Should Take It?

The human immunodeficiency virus, or HIV, is a virus that attacks the immune system and makes it hard for the body to fight off infections. It also impacts many, as experts estimate that nearly 1.2 million people in the United States have HIV, with 13 percent not even knowing they have it.

Though anyone can contract HIV, the condition devastated the LGBTQ+ community in the '80s and '90s, as it became the leading killer of men ages 25-44 at one point in the United States. But while HIV/AIDS continues to have a disproportionate impact on queer people — particularly Black and Latino men and trans people — HIV is not exclusive to this demographic. Yet the legacy of the AIDs epidemic and its continued negative association with the queer community still fuel the stigma around HIV education and prevention to this day. So let's be clear: everyone, regardless of background or sexuality, needs to educate themselves on the virus and consider their risk of exposure.

One of the best, most effective preventative methods to contracting HIV is taking PrEP (pre-exposure prophylaxis), a prescribed medication that lowers your chance of getting the virus. The CDC reports that PrEP, when taken as prescribed, reduces the risk of getting HIV from sex by about 99 percent, and for those who use injectable drugs, it reduces the risk by at least 74 percent. These statistics prove anyone who is sexually active or is an intravenous-drug user should assess their risk for HIV and consider their options to prevent HIV.

Ahead, we discuss how HIV works, your risk level, what PrEP does exactly, and how to access it.

To understand how to prevent HIV, you also need to understand how the virus works. HIV is spread through sexual fluids (including semen, preseminal fluid, rectal fluids, and vaginal fluids), blood (via transfusion or needle sharing), as well as through pregnancy and breast milk, per the CDC.

HIV weakens the immune system by attacking T cells (the white blood cells that fight off infection), leaving those with HIV more susceptible to illness. HIV can develop into AIDS, but the two terms are not synonymous. HIV and AIDs mean different things, as someone with HIV is considered to have AIDS when the T-cell count falls to a certain level or if they develop one or more opportunistic infections — meaning infections that occur in people with compromised immune systems. With modern treatment, Mayo Clinic reports that most people who have HIV will not develop AIDS. However, without treatment, HIV can develop into AIDS in eight to 10 years.

Unlike how it may be portrayed, HIV is not a death sentence, nor does it mean you can't have a full, loving life. In fact, many people with HIV are able to manage the virus through antiretroviral treatment (ART), resulting in what's called an "undetectable viral load," per the Cleveland Clinic. This means that with daily treatment, HIV can be suppressed to undetectable levels, virtually eliminating the risk of transmission to sexual partners. If you've heard the slogan "undetectable = untransmittable" (sometimes styled as U=U), it's referring to this exact scientific research, signifying that if your HIV levels become undetectable, you can not transmit HIV to a partner.

PrEP is a prescribed medication, and you must be HIV negative prior to taking it in order for it to be effective, according to the National Library of Medicine. While HIV-prevention rates remain high with all three PrEP options, your doctor will look at your lifestyle and other factors (like assigned sex) to help determine which is the right option for you. Here are the three FDA-approved options, per the CDC.

The CDC considers PrEP to require a high level of adherence, meaning taking PrEP is a serious commitment part of a larger, comprehensive HIV-prevention plan you decide with your healthcare provider.

Yes, PrEP is safe, per the CDC. There are some common side effects like diarrhea, nausea, headache, fatigue, and stomach pain, but the CDC says these usually resolve. However, there are more serious side effects to taking PrEP that you should consider with your doctor.

If you experience any of the above side effects, you should tell your doctor immediately or seek medical attention.

If you are sexually active or use intravenous drugs, you should speak to a trusted healthcare provider about whether taking PrEP is the right option for you. However, HIV.gov lists the following several factors that may increase your risk of HIV. If any of the below apply to you, it could mean you should consider taking PrEP.

The CDC has a flow-chart resource to help you assess your risk for HIV and if you should consider PrEP.

You can get a PrEP prescription through your primary care provider, an ob-gyn, or an HIV specialist. Although PrEP coverage is required under the Affordable Care Act and the Department of Labor said that insured patients should not cover any costs associated with PrEP, prices remain high. Some employers have even challenged federal requirements for coverage, according to recent reporting from the AP.

That said, there are several programs that supply people with free or low-cost PrEP, including Ready, Set, PrEP, which helps people without health insurance, as well as many local health department initiatives for at-risk populations.

Bottom line: everyone should consider their risk for HIV and work with a healthcare provider to find out if PrEP is the right option for you. HIV/AIDS is not a "gay disease," and everyone of all genders, sexualities, and backgrounds needs to think about protecting themselves and their loved ones.

Sara Youngblood Gregory was a contributing staff writer for POPSUGAR Wellness. She covers sex, kink, disability, pleasure, and wellness. Sara serves on the board of the lesbian literary and arts journal, Sinister Wisdom. Her work has been featured in Vice, HuffPost, Bustle, DAME, The Rumpus, Jezebel, and many others. Sara's debut nonfiction work, "The Polyamory Workbook," about navigating ethical nonmonogamy, is out now.